Humans Being is my current favorite. I say "current" because, like all things guitar, that is bound to change! This is the mother load of awesome presets!!!
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Guitars: Strat PartsCasters (x2), 81 Ibanez Artist, 2012 Gibson Les Paul Studio, Epiphone ES-339 P-90 Pro Effects: Atomic AmpliFIRE, Avid 11R, Franklin ProDrive, Franklin F-Plex Delay, Line 6 M9