the amp models in the eleven rack operate like real world amps. if you run a real world amp that loud, you will run out of headroom and get compression. settings that high would probably make you deaf too.

i would make one of two adjustments:

1) run the amp at a lower setting like you would in the real world.

or

2) set the output of the drive pedals low so as to not push the amp much further than you need to. start at almost off and work your way up until you get as much gain as you want without compressing the amp model.

the cool thing about the eleven rack is that it CAN emulate a wide open amp with output tube distortion. that can be good or bad depending on if you like power tube distortion. many artists crank an amp in the studio just to get the tone you are trying to dial out.