In general it is preferable to a have two drives, with one drive dedicated to audio recording and playback. I am not a Mac guy, so no ideas there. But you can get Windows laptops with two drives (or the ability to install). Typically a SSD for the OS and a mechanical drive for the data.
Assuming you are looking at Protools 11 you can get all the compatibility information here:
http://avid.force.com/pkb/articles/en_US/compatibility/Pro-Tools-11-System-Requirements
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