Slightly off topic - but I have a 2 Notes Torpedo CAB that I use with the 11R. I tried it in the FX Loop but have been happier with it after the Output To Amp. I thought through the signal path of an analog rig - the speaker cab/mic are the very last pieces. As such, I have elected to use it there.

YMMV of course, but that's how I prefer it.
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Guitars:
Strat PartsCasters (x2), 81 Ibanez Artist, 2012 Gibson Les Paul Studio, Epiphone ES-339 P-90 Pro
Effects:
Atomic AmpliFIRE, Avid 11R, Franklin ProDrive, Franklin F-Plex Delay, Line 6 M9