OMG. Roberob, your a legend mate. I went throught the whole optimization with no luck so I changed everything back to standard settings. Thought Id better try your fix of a new cable and it actually worked. Im speachless. 2 weeks of loading and unloading drives, motherboard bioses......all for one lousy cable.
Even with the network connected, recording onto my main C drive and everything alse set wrong, I can still get clean playback with 16 tracks and multiple plugins. Finally, you da man!!!!