it's all about the IR if you are using the amplifire. you are better off picking a dark sounding IR to start with. if that isn't an option, roll off highs from 5.5khz or higher.
Agreed. The IR makes a huge difference. I have the exact same preset - same settings everywhere except the IR. I have the same settings within the cabinet block, just a different IR. The difference in tone between the Scumback speaker and the V30 is dramatic. The Scumback sounds AWESOME when I'm at home but the highs become a fizzy swirl in the mix of my band and my tone practically washes out. At home the V30 sounds dull and lifeless but in the mix of the band is nothing short of BRILLIANT!
To echo Ross, I have the high rolloff in the cabinet block at 5.5Khz. That also makes a huge difference.
To me, the AmpliFIRE is the 11R in a pedal form with the added feature of choosing your own IR. They both have a meat and potatoes offering in terms of amp models and effects - but are excellent value for the dollar.
Once you get the right IR - that AmpliFIRE is just incredible!
YMMV - but that's been my experience.